In vitro Anti-arthritic and Hemolytic Activity of Leaf Extracts of Tragia involucrata

نویسندگان

  • Vinodhini Velu
  • Himaja Malipeddi
چکیده

Tragia involucrata commonly known as Indian stinging nettle is a shrub widely used in traditional ayurvedic system for treatment of cephalagia, skin infections, eczema, and bronchitis. However, in use as a traditional medicine since ancient time, its anti-arthritic and hemolytic properties are not yet studied. The present study aimed to assess the phytochemical analysis, in vitro anti-arthritic and hemolytic activity of the petroleum ether, chloroform, ethyl acetate and aqueous extracts of Tragia involucrate. The phytochemical analysis reveals the presence of phytoconstituents such as phenols, flavanoids, sterols and terpenoids etc. The maximum inhibition of anti-arthritic activity of 93% at the concentration of 200μg/ml was observed in chloroform extract. The hemolytic activity of the extracts on human erythrocytes was performed by standard method and the extracts were found to be non-hemolytic against the red blood cell membranes.

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تاریخ انتشار 2015